Canine Ceroid Lipofuscinosis, a Model for Ageing of the Human Isocortex
1984
In canine ceroid lipofuscinosis (one case studied), isocortical layer Illab pyramidal cells develop spindle-shaped enlargements of their proximal axon filled with lipopigment, a feature that can be observed in juvenile and adult type of human neuronal ceroid lipofuscinosis and in normal ageing of the human isocortex as well.
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