Carnitine palmitoyltransferase 2 (CPT2) knockout potentiates palmitate-induced insulin resistance in C2C12 myotubes.

Michael L. Blackburn,Kikumi D. Ono-Moore,Hany F. Sobhi,Sean H. Adams

Carnitine palmitoyltransferase 2 (CPT2) knockout potentiates palmitate-induced insulin resistance in C2C12 myotubes.

2020

Michael L. Blackburn
Kikumi D. Ono-Moore
Hany F. Sobhi
Sean H. Adams

Saturated fatty acids (SFAs) are implicated in muscle inflammation/cell stress and insulin resistance, but the catalog of factors involved is incomplete. SFA derivatives that accumulate with mismat...

Keywords:

Endocrinology
Internal medicine
Insulin resistance
Lipotoxicity
Myogenesis
Biology
C2C12
Diabetes mellitus
saturated fatty acid
Carnitine palmitoyltransferase 2
cell stress

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