Calcium in tumour metastasis: new roles for known actors.

Natalia Prevarskaya,Roman Skryma,Yaroslav Shuba

Calcium in tumour metastasis: new roles for known actors.

2011

Natalia Prevarskaya
Roman Skryma
Yaroslav Shuba

The ubiquitous second messenger Ca2+ is a crucial regulator of cell migration. This Review discusses recent data on ORAI1, STIM1 and TRP, which have been implicated in tumour cell migration and the metastatic cell phenotype.

Keywords:

Cell
Cell biology
Immunology
Phenotype
Calcium channel
Transient receptor potential channel
Second messenger system
Cell migration
Regulator
ORAI1
Biology
Calcium
STIM1
Tumour metastasis

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