12-Lipoxygenase is a Critical Mediator of Type II Pneumocyte Senescence, Macrophage Polarization and Pulmonary Fibrosis after Irradiation

Eun Joo Chung,Jessica L. Reedy,Seokjoo Kwon,Shilpa S. Patil,L. Valle,Ayla O. White,Deborah Citrin

12-Lipoxygenase is a Critical Mediator of Type II Pneumocyte Senescence, Macrophage Polarization and Pulmonary Fibrosis after Irradiation

2019

Eun Joo Chung
Jessica L. Reedy
Seokjoo Kwon
Shilpa S. Patil
L. Valle
Ayla O. White
Deborah Citrin

Radiation-induced pulmonary fibrosis (RIPF) is a chronic, progressive complication of therapeutic irradiation of the thorax. It has been suggested that senescence of type II pneumocytes (AECIIs), a...

Keywords:

Biochemistry
Lipoxygenase
Type-II Pneumocytes
Macrophage polarization
Senescence
Type II pneumocyte
Cancer research
Biology
Mediator
Pulmonary fibrosis

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