OPRM1 rs1799971 - COMT rs4680 - FAAH rs324420 genes interact with placebo procedures to induce hypoalgesia

AbstractGenetics studies on the placebo hypoalgesic effect highlight a promising link between single nucleotide polymorphisms (SNPs) in the dopamine, opioid, and endocannabinoid genes and placebo hypoalgesia. However, epistasis and replication studies are missing. In this study, we expanded on previ