Влияние функциональных проб на вариабельность сердечного ритма у больных бронхиальной астмой

An analysis of influence of functional tests (6 or 12 breathings per minute) and inhaled fenoterol on the heart rate variability (HRV) was performed in 64 moderate bronchial asthma (BA) patients with subsiding exacerbation and in 42 healthy individuals. We evaluated FEV 1 , PEF, FEF 50 , FEF 75 and HRV using the frequency analysis. Enhanced sympathetic (in the 6 breathings per minute test) and parasympathetic influences (in the 12 breathings per minute test) on the chronotropic cardiac function were noted. The sympathetic influence on the heart rate after the inhalation of fenoterol was shown in the BA patients. Combination of both the tests allowed to reveal latent disturbances of the sympathetic and parasympathetic components of the heart rate regulation in the BA patients (relative sympathetic and parasympathetic insufficiency). A reliable correlation was found between the parameters of the bronchial passability and HRV, which permitted to assume a united neuro-vegetative regulation of the cardiac-and-respiratory system.