Demonstration of collagenase activity in rat liver homogenate.
1974
Abstract Collagenase activity became detectable in rat liver homogenate by washing liver tissue repeatedly with buffered saline before homogenization. This enzyme activity was inhibited by adding minute quantities of serum. These data suggest that collagenase is active in situ in the liver, but is made inactive during the homogenization by forming a complex with contaminating serum factors.
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