Doxorubicin triggers splenic contraction and irreversible dysregulation of COX and LOX that alters the inflammation-resolution program in the myocardium

Jeevan Kumar Jadapalli,Griffin W. Wright,Vasundhara Kain,Mohammad Asif Sherwani,Ravi Sonkar,Nabiha Yusuf,Ganesh V. Halade

Doxorubicin triggers splenic contraction and irreversible dysregulation of COX and LOX that alters the inflammation-resolution program in the myocardium

2018

Jeevan Kumar Jadapalli
Griffin W. Wright
Vasundhara Kain
Mohammad Asif Sherwani
Ravi Sonkar
Nabiha Yusuf
Ganesh V. Halade

Doxorubicin (DOX) triggered splenic mass loss and decreased CD169 with germinal center contraction in acute and chronic exposure. The cardiac toxicity of DOX is marked with dysregulation of immunom...

Keywords:

Inflammation
Cancer research
Doxorubicin
Biochemistry
Contraction (grammar)
Germinal center
Cardiac toxicity
Cyclooxygenase
Diabetes mellitus
Lipoxygenase
Biology
inflammation resolution

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