Association between geriatric assessment findings and clinical depression in 1092 older patients with cancer: The ELCAPA Cohort study.

1574 Background: Few studies assessed jointlygeriatric and oncological factors associated with clinical depression in geriatric oncology setting. To assess the prevalence and associated factors of clinical depression in older patients with cancer. Methods: We studied a prospective cohort of cancer patients aged ≥ 70 years and referred to geriatric oncology clinics between 2007 and 2012. A multidimensional geriatric assessment (GA) was performed before treatment. Clinical depression was diagnosed by senior geriatricians by a semi-structured interview. It encompassed criteria of the Diagnostic and Statistical Manual of Mental Disorders (4th edition, DSM-IV) and of the International Classification of Diseases (10thedition, ICD-10). Multivariate analysis was based on multivariate logistic models. Systematic adjustement for gender was done. Results: Of 1121 consecutive patients, 1092 had available data (mean age, 80.4 years; women, 48.8%; metastases, 51.3%; cancer location: colorectal 21.1%, breast 16.8%, kidn...