Monitoring chronic myeloid leukemia (CML) response to tyrosine kinase inhibitors (TKI) and homoharringtonine (HHT) using peripheral blood (PB) fluorescence in situ hybridization (FISH) and quantitative RT-PCR (Q-PCR): Are bone marrow biopsies still needed?

H.J. Khoury,Lisa Lima,Debra Saxe,Karen P. Mann,Martha Arellano,Leonard T. Heffner,Leon Bernal-Mizrachi,Morgan L. McLemore,Amelia Langston,Winton Ef

Monitoring chronic myeloid leukemia (CML) response to tyrosine kinase inhibitors (TKI) and homoharringtonine (HHT) using peripheral blood (PB) fluorescence in situ hybridization (FISH) and quantitative RT-PCR (Q-PCR): Are bone marrow biopsies still needed?

2009

H.J. Khoury
Lisa Lima
Debra Saxe
Karen P. Mann
Martha Arellano
Leonard T. Heffner
Leon Bernal-Mizrachi
Morgan L. McLemore
Amelia Langston
Winton Ef

7064 Background: The purpose of this study is to compare simultaneously obtained PB and bone marrow (BM) BCR-ABL FISH and Q-PCR to monitor response to TKI and HHT in CML. Methods: Between January 2...

Keywords:

Bone marrow
Tyrosine kinase
Cancer research
Fluorescence in situ hybridization
Peripheral
Myeloid leukemia
Homoharringtonine
Real-time polymerase chain reaction
Medicine
Pathology
peripheral blood

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