Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats

Keyan Chen,Nan Wang,Yugang Diao,Wanwei Dong,Yingjie Sun,Lidan Liu,Xiuying Wu

Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats

2017

Keyan Chen
Nan Wang
Yugang Diao
Wanwei Dong
Yingjie Sun
Lidan Liu
Xiuying Wu

Background/Aims: Cardiopulmonary bypass (CPB) is prone to inducing brain injury during open heart surgery. A hydrogen-rich solution (HRS) can prevent oxidation an

Keywords:

PI3K/AKT/mTOR pathway
Biochemistry
Protein kinase B
Saline
Inflammation
Cardiopulmonary bypass
Apoptosis
Signal transduction
Diabetes mellitus
Biology
Pharmacology
Phosphorylation
Evans Blue
Western blot

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