Accelerated displacement of duplex DNA strands by a synthetic circular oligodeoxynucleotide

Thomas A. Perkins,Joshua L. Goodman,Eric T. Kool

Accelerated displacement of duplex DNA strands by a synthetic circular oligodeoxynucleotide

1993

Thomas A. Perkins
Joshua L. Goodman
Eric T. Kool

A small circular synthetic DNA oligomer 34 bases in size binds to duplex DNA and actively displaces one of the strands at a rate significantly faster than unassisted dissociation of the duplex.

Keywords:

DNA clamp
Replisome
Heavy strand
Biophysics
Chemistry
DNA polymerase
Nucleic acid thermodynamics
Base pair
DNA ligase
Inorganic chemistry
Duplex (building)
Molecular biology

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