Changes in phosphoinositide metabolism in the brain of rats with different neuromuscular excitation threshold subjected to neurotic exposure and antioxidant administration

: No difference was found in metabolism of phosphoinositides in rats with high (H) and low (L) levels of excitability under normal conditions. Neurotisation decreased the content of phosphotidilinositol-4,5-diphosphate and increased the phosphorus turnover rate in the brain cortex of the L rats. Oxymetacyl reduced the effect of neurotisation. This antioxidants seems to exert an effect on the brain cells functional condition in the L rats.