Síndrome hemofagocítico secundario en el recién nacido

El sindrome hemofagocitico secundario o reactivo es una entidad poco frecuente, de etiologia multifactorial, que clinicamente se manifiesta como un cuadro grave y de alta letalidad. Se caracteriza por activacion benigna de los macrofagos, asociada a infecciones virales, bacterianas, fungicas o parasitarias, a inmunodeficiencias y a neoplasias. Se presenta el caso clinico de un neonato varon, de 17 dias de vida, que presento fiebre, manifestaciones catarrales y digestivas. Evoluciono clinicamente con ictericia, hepatoesplenomegalia, trombocitopenia y anemia. Se diagnostico un citomegalovirus en la orina. Egreso vivo a los 68 dias de vida, con regresion del cuadro clinico The secondary or reactive hemophagocytosis syndrome is an uncommon entity clinically manifested by a severe clinical picture and a high mortality rate. It is characterized by a macrophages benign activation, associated with viral, bacterial, fungoid or parasitic infections and immunodeficiencies and neoplams. This is the clinical case of a 17 days male neonate with fever, suffering from cold and digestive manifestations who clinically evolving with jaundice, hepatosplenomegaly and anemia. A cytomegalovirus was diagnosed in urine. Was discharged being alive at 68 days with a regression of clinical picture