Estimation of some immunological parameters and trace element in patients with head injury

Objective: Trauma is the result of several kinds of accidents such as crashes of vehicles but mostly, in certain conditions, military operations and the effects of explosions can cause head injury. Interleukins and some trace elements have a role in head injury patients. this study was conducted to clarify the effect of serum IL-10, IL-18 and selenium levels in head injury patients. Materials and Methods:Our study included 60 patients with head injury who were attending the Neurosurgical Teaching Hospital in Baghdad. Their ages ranged 20-50 years matched to 30 healthy volunteers. Blood samples were collected about fourteen hours after injury. ELISA and AAS methods were used to measure serum ILs and Se respectively. Results: serum level of IL-10 was 93.8 ± 29.4 pg/mL and of IL-18 was 281.19 ± 31.77 pg/mL in patients, which were higher significant than those in the control group (51.8 ± 21.9and 189.43 ± 15.32 pg/mL, respectively). Selenium levels in patients with head injury was 0.117 ± 0,02 µg/mL, which was higher significant than that recorded in the control group(0.034 ± 0.005µg/mL).Objective: Trauma is the result of several kinds of accidents such as crashes of vehicles but mostly, in certain conditions, military operations and the effects of explosions can cause head injury. Interleukins and some trace elements have a role in head injury patients. this study was conducted to clarify the effect of serum IL-10, IL-18 and selenium levels in head injury patients. Materials and Methods:Our study included 60 patients with head injury who were attending the Neurosurgical Teaching Hospital in Baghdad. Their ages ranged 20-50 years matched to 30 healthy volunteers. Blood samples were collected about fourteen hours after injury. ELISA and AAS methods were used to measure serum ILs and Se respectively. Results: serum level of IL-10 was 93.8 ± 29.4 pg/mL and of IL-18 was 281.19 ± 31.77 pg/mL in patients, which were higher significant than those in the control group (51.8 ± 21.9and 189.43 ± 15.32 pg/mL, respectively). Selenium levels in patients with head injury was 0.117 ± 0,02 µg/mL, which wa...