Topography, Wettability, and Electrostatic Charge Consist Major Surface Properties of Intraocular Lenses.

ABSTRACTPurpose: To quantify potential relevant factors that affect the biocompatibility and functionality of intraocular lenses (IOLs) by analyzing the surface properties of various IOL materials.Methods: Eleven IOL models with the same dioptric power made by different manufacturers were studied. The IOLs were made of poly-methyl methacrylate (PMMA), hydrophobic acrylate, hydrophilic acrylate, and silicone. The IOL surface topography was evaluated using atomic force microscopy (AFM). Surface potential was measured by electric force microscopy (EFM). Surface wettability was assessed with the water contact angle using the sessile drop method.Results: The PMMA IOLs had statistically significant surface irregularities with the highest surface roughness values while the silicone and hydrophilic acrylic IOLs had the lowest values. Surface potentials on IOLs revealed that all IOL models made of PMMA had positive charge. The hydrophobic acrylic IOL had a significantly higher positive charge (6.2v ± 0.1v), while ...