Impact of CYP2C19 phenotypes on escitalopram metabolism and an evaluation of pupillometry as a serotonergic biomarker

Lene Noehr-Jensen,Stine Thorhauge Zwisler,F. Larsen,Søren Hein Sindrup,Per Damkier,Flemming Nielsen,Kim Brøsen

Impact of CYP2C19 phenotypes on escitalopram metabolism and an evaluation of pupillometry as a serotonergic biomarker

2009

Lene Noehr-Jensen
Stine Thorhauge Zwisler
F. Larsen
Søren Hein Sindrup
Per Damkier
Flemming Nielsen
Kim Brøsen

Purpose To investigate the impact of cytochrome P450 2C19 (CYP2C19) phenotypes on escitalopram metabolism and to evaluate pupillometry as a serotonergic biomarker.

Keywords:

Escitalopram
Pupillometry
Serotonin
Biomarker (medicine)
CYP2C19
Serotonergic
Endocrinology
Biology
Internal medicine
Medicine
Metabolism
Pharmacology
Phenotype
Reuptake inhibitor

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