Synthesis of new compounds in the series of aryl-substituted ureas with cytotoxic and antioxidant activity
2020
A series of aryl-substituted ureas and carbamates containing chlorinated aromatic and modified imidazolidinone moieties were synthesized. These compounds were found to be cytotoxic to breast cancer cell line MDA-MB-231, glioblastoma U-87 MG and neuroblastoma SH-SY5Y, but not to melanoma A-375.
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