Different Chemotherapy Regimens for Advanced Non-small Cell Lung Cancer: Cost-Effect Analysis

OBJECTIVE:To observe and compare the rationality among three combined chemotherapy regimens-TC(TAX+CBP),GP(GEM+DDP) and NP (NVB+DDP) from the perspective of pharmacoeconomics. METHODS: Fifty patients were enrolled in this study, 18 were assigned to TC group, 16 NP group and another 16 GP group. RESULTS: The effective rates of TC, NP and GP groups were 44.4%, 37.5% and 50.0%, respectively, and the short-term therapeutic efficacies among three groups showed no statistical difference. The major toxicities wrere bone marrow suppression and gastrointestinal tract reactions. The cost-effectiveness ratios were 410.33, 362.63 and 313.05, respectively. CONCLUSION: GP is more satisfactory in curative efficacy and tolerable in its toxicity, and it is currently one of the first choices for the treatment of NSCLC.