Clinical outcomes after Selective renal artery embolization combined with DynaCT-guided Microwave ablation for T1a Renal Cell Carcinoma: Case series

Abstract Introduction Microwave ablation(MWA) is well recommended for RCC, image guided ablation has increasingly been combined with computer-assisted stereotactic navigation. In this case series, we aim to analyze clinical outcomes of selective renal artery embolization (RAE) combined with DynaCT-guided MWA in the treatment of small renal cell carcinoma(RCC) Methods We retrospectively reviewed the medical records of 27 consecutive patients with RCC (≤4 cm) received RAE combined with simultaneous DynaCT-guided MWA. The overall survival, progression-free survival, surgery-related complications and renal function changes were analyzed. Results The technical success rates was 100%. The duration of ablation was 5 (4-7) minutes and the generator power was 55 (45-60) watts. There were no life-threatening complications related to the procedures though one instance of abscess, one of renal failure, one of subcapsular hematoma and two of hematuria were seen after MWA. The mean GFR 1 month after treatment was significantly decreased, which was comparable to that 3 months. The 1-, 3-, and 5-year progression-free survival rates and overall survival rates were 100.0%, 96.3%, 85.2% and 100.0%, 100.0%, 92.6% respectively. Conclusions The result of the present study at 5-year mean follow up showed that DynaCT-guided MWA+ RAE is a safe and effective method for the treatment of early renal tumors, which usually provides an accurate tumor puncture path and better clinical outcomes.