Detection Tete per-operative able to be coupled to an excision tool

The invention relates to a probe (2) Intraoperative for guiding an excision tool, comprising a head (21) of detection, said detection head comprising: - at least one optical fiber (2121, 2123) adapted to receive and guiding a signal transmitted by a tissue area to equipment (32) for analysis, - means (2112) for attachment to secure the head (21) on the tool (1) excision, so that the tool (1) excision is adapted to extract a portion of tissue in the tissue area emitting the signal.