Polymer-single-crystal@nanoparticle nanosandwich for surface enhanced Raman spectroscopy

We report a novel polymer-single-crystal@gold nanoparticle (PSC@AuNP) nanosandwich (two layers of AuNPs sandwiching one layer of PSC) structure for surface enhanced Raman spectroscopy (SERS). It can be used in the conventional way through solution mixing with analytes or by adopting tip-enhanced Raman spectroscopy (TERS) configuration by directly applying onto a flat or curved substrate for surface detection.