Search for Carcinogenic Agents in the Shanghai Rubber Industry

Preliminary studies on crude cancer incidences (1961–1970) among workers of 89 factories in Shanghai revealed excessive cancer risks to workers in certain rubber tyre factories. Three 2-year in situ animal exposures staged in the First Workshop of Rubber Tyre Factory A showed that compounding and banbury mills for mastication and mixing were the origins of carcinogenic pollutants. These results prompted reconstruction of the workshop and suspension of the use of antioxidant D in Shanghai.