Assessment of sFas concentration in serum of uveitis patients

PURPOSE: To evaluate the concentration of sFas in serum of uveitis patients. MATERIAL AND METHODS: Serum samples were collected from 13 patients with uveitis and 12 controls. All patients have underwent ophthalmic and laboratory examinations. The sFas levels were determined by immunoenzymatic assay ELISA. RESULTS: We found statistically increased levels of sFas in serum of patients with uveitis compared with controls. CONCLUSIONS: Our results suggest a systemic nature of uveitis with persistent activation of the immune system. Apoptosis may play regulatory role in ocular inflammation of patients with uveitis.