D-DIMERS IN THE DIAGNOSIS OF PULMONARY EMBOLISM

D-Dimers, endogenous fibrinolysis markers, represent the most determined laboratory test of fibrinolysis and coagulation tests. Their role in the diagnosis of pulmonary embolism was extensively discussed and analysed. Currently, there is an important literature which emphasized these markers and which suggests that their clinical indications have not been fully investigated, new utilities to be indicated in the near future. I brought up the main features of D-Dimers, their contribution in the current practice, their limits and future prospects, in the light of the latest literature data. Cuvinte cheie: D- dimeri, trombembolism pulmonar, fibrinoliză Rezumat: D-dimerii, markeri ai fibrinolizei endogene, reprezintă cel mai determinat test de laborator la ora actuală dintre testele de coagulare si fibrinoliz ă. Rolul lor in diagnosticul TEP a fost indelung discutat si analizat; la ora actuală există o literatur ă impresionantă ce subliniază importanţa acestor markeri, si care ne sugerează că indicaţiile lor clinice nu au fost total investigate, urmând ca in viitorul apropiat să ne fie sugerate noi utilităţi ale acestora. Am readus in discuţie principalele caracteristici ale D-Dimerilor, aportul lor in practica curentă, limitele lor si perspectivele viitoare, in lumina ultimelor date din literatura de specialitate.