AGR2 Is a Novel Surface Antigen That Promotes the Dissemination of Pancreatic Cancer Cells through Regulation of Cathepsins B and D

Laurent Dumartin,Hannah J. Whiteman,Mark E. Weeks,Deepak Hariharan,Branko Dmitrovic,Christine A. Iacobuzio-Donahue,Teresa A. Brentnall,Mary P. Bronner,Roger Feakins,John F. Timms,Caroline H. Brennan,Nicholas R. Lemoine,Tatjana Crnogorac-Jurcevic

AGR2 Is a Novel Surface Antigen That Promotes the Dissemination of Pancreatic Cancer Cells through Regulation of Cathepsins B and D

2011

Laurent Dumartin
Hannah J. Whiteman
Mark E. Weeks
Deepak Hariharan
Branko Dmitrovic
Christine A. Iacobuzio-Donahue
Teresa A. Brentnall
Mary P. Bronner
Roger Feakins
John F. Timms
Caroline H. Brennan
Nicholas R. Lemoine
Tatjana Crnogorac-Jurcevic

A prometastatic protein expressed on the cell surface of aggressive pancreatic cancers has features of an appealing theranostic target to improve management of this disease.

Keywords:

Ovarian cancer
Cathepsin D
Cell
Immunology
Pancreatic cancer
Antigen
AGR2
Cancer research
Cathepsin B
Biology
Adenocarcinoma

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