Platelet function during antihypertensive treatment with quinapril, a novel angiotensin converting enzyme inhibitor

The aim of the present study was to examine the effect of antihypertensive treatment with quinapril, a novel ACE inhibitor not containing a sulfhydryl group, on platelet function. Ten white men (age range of 32-61 years) with untreated mild-to-moderate essential hypertension (supine diastolic blood pressure >95 mm Hg) were treated with 4 weeks each of placebo and quinapril in a double-blind, randomized, crossover design.