Total Functional Score of Enhancer Elements Identifies Lineage-Specific Enhancers That Drive Differentiation of Pancreatic Cells

Venkat S. Malladi,Anusha Nagari,Hector L. Franco,W. Lee Kraus

Total Functional Score of Enhancer Elements Identifies Lineage-Specific Enhancers That Drive Differentiation of Pancreatic Cells

2020

Venkat S. Malladi
Anusha Nagari
Hector L. Franco
W. Lee Kraus

The differentiation of embryonic stem cells into various lineages is highly dependent on the chromatin state of the genome and patterns of gene expression. To identify lineage-specific enhancers dr...

Keywords:

Regulation of gene expression
Genome
Biology
Chromatin
Embryonic stem cell
Cell biology
Gene expression
Computational biology
Enhancer
Transcription factor
Epigenome

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