Abstract 17456: Early Repolarization is Associated With Resuscitated Sudden Cardiac Arrest but not Autopsy-Proven Sudden Arrhythmic Death

Introduction: Association between early repolarization (ER) on ECG and sudden cardiac arrest (SCA) risk has been suggested by epidemiologic studies with variable prognostic results. This association has not been investigated in autopsy-proven sudden cardiac deaths (SCDs). Methods: All pre-arrest ECGs performed as part of medical care were obtained and reviewed for ER on all resuscitated SCAs and all out-of-hospital (OOH) SCDs in San Francisco (SF) between 2/1/2011 and 3/1/2014 captured through active surveillance of all deaths reported to the Office of the Chief Medical Examiner as part of the SF Postmortem Systematic Investigation of Sudden Cardiac Death (POST SCD) study. All contemporaneous citywide resuscitated SCAs were identified via responding SF Fire Department paramedic records and cause of death was adjudicated after review of autopsy, toxicology, histology, and medical records. ER was defined as elevation of QRS-ST junction ≥ 0.1mV in ≥ 2 contiguous inferior or lateral leads, manifesting as end-...