Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).
2014
Abstract The exploration of a diarylsulfonamide series of free fatty acid receptor 4 (FFA4/GPR120) agonists is described. This work led to the identification of selective FFA4 agonist 8 (GSK137647A) and selective FFA4 antagonist 39 . The in vitro profile of compounds 8 and 39 is presented herein.
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