A concise and scalable formal synthesis of the enantiopure side-chain diester of homoharringtonine

Moran Sun,Xin Jia,Yaowen Lai,Hua Yang

A concise and scalable formal synthesis of the enantiopure side-chain diester of homoharringtonine

2015

Moran Sun
Xin Jia
Yaowen Lai
Hua Yang

The enantiopure side-chain diester of homoharringtonine (HHT) has been prepared in 38% overall yield, from cheap L-aspartic acid by a linear sequence of 10 chemical operations (mean yield per step:...

Keywords:

Side chain
Organic chemistry
Enantiopure drug
Homoharringtonine
Chemistry
formal synthesis
Regioselectivity
linear sequence

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations