Association between Menopausal Hormone Therapy and Incidence of Psoriasis: A Secondary Analysis from the Women's Health Initiative Randomized Clinical Trials.

Estrogen level fluctuations have been linked to psoriasis (1); however, the association between menopausal hormone therapy and risk of psoriasis is largely unexplored. We analyzed data from the Women's Health Initiative's (WHI) randomized controlled trials comparing conjugated equine estrogens (CEE) vs. placebo and CEE plus medroxyprogesterone acetate (MPA) vs. placebo to investigate the association between hormone therapy use and psoriasis.