Applicative value of chest HRCT for bronchiectasis evaluating in pulmonary infection withpseudomonas aeruginosain patients with cystic fibrosis

Aim: Elucidation of bronchiectasis by chest HRCT in patients with cystic fibrosis (CF) in relation to pulmonary infection with Ps.aeruginosa. Methods: The study includes 45 patients with CF monitored at the Cystic Fibrosis Center at Mother and Child Institute, which were imagistic examined by lung CT for evaluating the bronchopulmonary changes (80-slice CT-scanner Aquilion Prime, Toshiba). The diagnosis of CF was confirmed by a sweat test (Macroduct, USA), and by CFTR mutation. Results: Imagistic researches by CT were performed on CF patients who presented the chronic and recurrent symptoms of bronchopulmonary infections.Only in 15% cases, finding the imagistic minor changes - the signs of bronchitis, light hyperinflation, focal areas of “ground glass”.The most of CF patients (60%) had sacciforme bronchiectasis predominantly localized in the right upper lobe, but in 1/3 cases were extended bilaterally.Tubal bronchiectasis were visualized in 24,4% of CF patients.Pneumatocele and air cysts (diameter of 3 cm to 8 cm) with the location in upper lobes were found in 15% of cases, exclusive in adult patients and teenagers. In 11,1% of CF patients have been identified in the lung fibroatelectasis with frequent location right medium lobe.All CF patients with bronchiectasis were diagnosed with pulmonary infection with Ps.aeruginosa . Conclusion: CT lung is a highly informative imagisticmethod for evaluating the pulmonary changes in patients with CF, which are dominated by bronchial deformations with sacciform character, especially in patients with lung infection with Ps.aeruginosa .