Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis

K.S. Tølbøl,Birgit Stierstorfer,Jörg F. Rippmann,Sanne S. Veidal,K. Rigbolt,Tanja Schönberger,Matthew P. Gillum,Henrik H. Hansen,Niels Vrang,Jacob Jelsing,Michael Feigh,Andre Broermann

Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis

2019

K.S. Tølbøl
Birgit Stierstorfer
Jörg F. Rippmann
Sanne S. Veidal
K. Rigbolt
Tanja Schönberger
Matthew P. Gillum
Henrik H. Hansen
Niels Vrang
Jacob Jelsing
Michael Feigh
Andre Broermann

Background There is a marked need for improved animal models of nonalcoholic steatohepatitis (NASH) to facilitate the development of more efficacious drug therapies for the disease.

Keywords:

Endocrinology
Medicine
Internal medicine
Diabetes mellitus
Steatohepatitis
Disease
Cholesterol
Elafibranor
Fibrosis
Gene expression
Hepatology
Obeticholic acid

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