Massive myocardial infarct with healthy coronary arteries caused by ostial thrombosis

: Report of an exceptional case of massive anterior-wall myocardial infarction ending in death in a man aged 42, with no previous coronary history nor risk factors of atherosclerosis. Autopsy has demonstrated a thrombus obliterating the coronary artery ostium, penetrating into the first centimetre of the common trunk, while the coronary network was otherwise normal. The nature of this thrombus remains unexplained and did not seem to be of embolic origin.