IDDF2020-ABS-0155 A new diagnostic index of sarcopenia for predicting short-term postoperative complications in patients undergoing surgery for gastric cancer

Background Patients with gastric cancer usually have weight loss, sarcopenia and malnutrition. Serum creatinine/cystatin C (CCR) is a new, simple, easily measured tool that could serve as a biomarker of sarcopenia. The purpose of our study was to assess the predictive ability of preoperative CCR for short-term prognosis in patients with gastric cancer undergoing surgery. Methods This retrospective study included 309 patients with gastric cancer undergoing surgery. Univariate and multivariate analyses were performed to identify risk factors. Patients were divided into two groups according to the optimal cut-off value of CCR. The clinical association of CCR with characteristics and postoperative complications was evaluated. Results Among all the patients, age, lymphocyte count and cystatin C (CysC) level were independent risk factors, while red blood cell (RBC) count and CCR were independent protective factors for short-term postoperative complications in gastric cancer patients undergoing surgery. The preoperative CCR showed a good predictive ability for short-term postoperative complications, with an optimal cut-off value of 7.117. Patients with low CCR had a higher incidence of overall complications (P Conclusions The preoperative CCR was identified as a reliable nutrition and sarcopenia assessment tool for predicting short-term prognosis for patients with gastric cancer after surgery.