Initial results from a first in human trial incorporating accelerated dose titration of a novel immune stimulating oncolytic virus - VG161.

Ronghua Zhao,Rasha Cosman,Neha Aggarwal,Aaron OGrady,Eugene Hsu,Luke Ardolino,Huiqun Xia,Yiting Chi,Shi Qui,Yanal M. Murad,Erica Lee,William Jia,Anthony M. Joshua

Initial results from a first in human trial incorporating accelerated dose titration of a novel immune stimulating oncolytic virus - VG161.

2021

Ronghua Zhao
Rasha Cosman
Neha Aggarwal
Aaron OGrady
Eugene Hsu
Luke Ardolino
Huiqun Xia
Yiting Chi
Shi Qui
Yanal M. Murad
Erica Lee
William Jia
Anthony M. Joshua

e14574Background: Oncolytic virus (OV) can specifically replicate in cancer cells causing cell lysis. Together with the expression of immune stimulating payloads, OV can induce an anti-tumor immune...

Keywords:

Cancer research
Immune system
first in human
Oncolytic virus
Medicine
dose titration
Cancer cell
Lysis

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