MECHANISMS OF HYPERTENSION FOLLOWING VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITION: THE HYPAZ TRIAL
2016
Vascular endothelial growth factor (VEGF) promotes nitric oxide activity. VEGF inhibitors are anti-cancer drugs that often cause hypertension but mechanisms are unclear. We hypothesised that VEGF inhibition leads to endothelial dysfunction, thus increasing blood pressure.
27 normotensive cancer
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