Copper-catalyzed redox neutral ketoalkylation of Csp2–H bonds via C–C bond cleavage

An efficient copper-catalyzed ketoalkylation of Csp2–H bonds with cycloalkyl silyl peroxides under mild and redox neutral conditions is presented. Relying on the C–C bond cleavage, a series of distal ketoalkyl moieties were successfully incorporated into the specific position of quinoxalin-2(1H)-ones, heteroaromatic N-oxides and quinones with moderate to good yields.