Preparation method of trifloxystrobin

2014 
The invention discloses a preparation method of trifloxystrobin, and the preparation method comprises the following steps: with m-trifluoromethyl acetophenone oxime and (E)-2-(2'-bromomethyl phenyl)-2-methyl carbonyl acetate-O-methyl ketoxime as raw materials, adding the raw materials into a heterogeneous system consisting of an inorganic alkaline solution and an organic solvent; adding a catalyst for an etherification reaction; after the reaction, directly performing liquid separation operation to separate out an organic phase; reducing pressure, recrystallizing, filtering and drying to obtain the trifloxystrobin. Compared with the traditional technology, the method disclosed by the invention can be used for simplifying the aftertreatment operation and has the advantages of simplicity and easiness in operation, relatively high yield and relatively high content; by virtue of the use and recovery of solvent, the generation of wastewater is greatly reduced, the environmental pollution is reduced, and the production cost is lowered; by adopting a phase transfer catalyst in the reaction, the reaction speed is increased, the production cycle is shortened, and the method is suitable for industrial production.
    • Correction
    • Source
    • Cite
    • Save
    • Machine Reading By IdeaReader
    0
    References
    0
    Citations
    NaN
    KQI
    []