Chronic administration of buprenorphine in combination with samidorphan produces sustained effects in olfactory bulbectomised rats and Wistar-Kyoto rats:

Nikita N. Burke,Yan Li,Daniel R. Deaver,David P. Finn,Michelle Roche,David J. Eyerman,Connie Sanchez,John P. Kelly

Chronic administration of buprenorphine in combination with samidorphan produces sustained effects in olfactory bulbectomised rats and Wistar-Kyoto rats:

2019

Nikita N. Burke
Yan Li
Daniel R. Deaver
David P. Finn
Michelle Roche
David J. Eyerman
Connie Sanchez
John P. Kelly

Background:The combination of buprenorphine, a partial mu-opioid receptor agonist and a functional kappa-opioid receptor antagonist, with samidorphan, a functional mu-opioid receptor antagonist, is...

Keywords:

Psychology
Wistar Kyoto Rats
Samidorphan
Receptor antagonist
Anesthesia
Agonist
Behavioural despair test
Buprenorphine
Receptor
Pharmacology
Antidepressant
μ-opioid receptor

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