Bronquiolitis obliterante con neumonía organizada: forma poco frecuente de toxicidad pulmonar en el tratamiento radioterápico del cáncer de mama

The incidence of symptomatic pneumonitis in patients who had received radiation therapy for breast cancer is low (<1%). Recently, bronchiolitis obliterans organizing pneumonia (BOOP) syndrome has been described as a secondary lung toxicity due to the radiation therapy, which appears beyond the radiation field (migratory pneumonitis) and is triggered by hypersensitivity reactions mediated by eosinophils, neutrophils and lymphocytes.