Invertase 配合含嗽剤の使用による化学的 plaque control について

The purpose of the investigation was to evaluate the effects of invertase during an experimental period with the mouth wash.The subjects were ten dental students that had healthy gingiva; they were divided into three groups.The first group consisted of two students as controls; the second group of four students was administered 3 drops of (124units)/10ml invertase; the third group of four students was administered 10 drops of (412units)/10ml invertase.Before the study, the subjects practiced oral hygiene for a month, and then the experiment started.The students were ordered to rinse their mouth 10ml of solution for one minute, twice a day, during the two week period. They were also asked not to perform other oral hygiene procedures.The results were obtained as follows:(1) After the 3rd day observation on volume of plaque accumulation had become statistically significant. (p<0.01)(2) After 10 and 14 day periods, the statistical significance of the occurence of gingivitis had become (p<0.05) and (p<0.01), respectively.(3) Probing depth of the three groups was not statistically significant until the end of 14 days.(4) There were no side effects from invertase during the experimental period.