A method for inhibition of t-cell leukemia cells detected chimeric anti-cd19 antigen receptor

The present invention discloses a method of detecting anti-CD19 chimeric T cell antigen receptor inhibition method of leukemia cells: (1) mixing ratio of expressing chimeric anti-CD19 and T cell antigen receptors of leukemia cells transplanted into immune defect model in vivo mouse, accession number chimeric anti-CD19 T cell antigen receptor CCTCCNO: C201503; (2) staining of peripheral blood cells of the immunodeficient mouse model; (3) the peripheral blood cells by flow cytometry after staining instrument for testing. Advantage of the present invention is that the human leukemia cells and cells capable of inhibiting the development of their common transplanted into immunodeficient mice may reflect true inhibition of different human leukemia cells, to ensure efficient method for detecting inhibition , accuracy.