Optoelectronic tweezers for medical diagnostics
2012
Optoelectronic tweezers (OET) allows the spatial patterning of electric fields through selected illumination of a
photoconductive surface. This enables the manipulation of micro particles and cells by creating non-uniform
electrical fields that then produce dielectrophoretic (DEP) forces. The DEP responses of cells differ and can
produce negative or positive (repelled or attracted to areas of high electric field) forces. Therefore OET can be
used to manipulate individual cells and separate different cell types from each other. Thus OET has many
applications for medical diagnostics, demonstrated here with work towards diagnosing Human African
Trypanosomiasis, also known as sleeping sickness.
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