Tumor necrosis factor-α and interleukin-1β treatment of endometrial stromal cells does not promote their adhesion to peritoneal mesothelial cells in an in vitro model of early-stage endometriosis

In the present study, we developed an original and reproducible quantitative in vitro model of endometrial cell adhesion to peritoneal mesothelial cells in order to better assess the impact of pro-inflammatory cytokines on early-stage endometriosis development. We demonstrated that pre-treatment with TNF-α and IL-1β does not promote endometrial stromal cell adhesion to peritoneal mesothelial cells.