GHRELIN ENDOCRINE CELLS IN THE HUMAN STOMACH DURING PRENATAL AND EARLY POSTNATAL DEVELOPMENT
2011
The aim of this study was to investigate the appearance, localization and
density of ghrelin cells in the human stomach during prenatal development.
For this purpose the antrum and corpus of embryos, fetuses and infants are
stained immunohistochemically by the streptavidin-biotin technique. The
presence of P/D1 cells at 11 weeks of fetal development, their highest
density during the first detection and higher density in the corpus than in
antrum, and their localization in the glandular base of stomach gland, all
suggest that ghrelin plays a major role in the early stages of the developing
stomach.
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