THE HYPOGLYCEMIC EFFECT OF SOME COMMON PLANTS THAT GROW IN EGYPT

The study aimed to study, the chemical composition of lupine (bitter and sweet) seeds and fenugreek seeds and their content of active chemicals that have a hypoglycemic effect and also the effect of lupine (bitter and sweet) seeds powdere and fenugreek seeds powder and the combination of bitter lupine (10%) and fenugreek (10%) on the increase of glucose level, enzymes, indications (liver, kidneys, lipid and antioxidants activity) and liver tissues in diabetic rats induced-alloxan. The addition of 20% of lupine (bitter and sweet) seeds powder, fenugreek seeds powder, and the combination of bitter lupine (10%) and fenugreek (10%) with a diet meal for diabetic rats led to decrease of glucose level, enzymes and indications of (liver, kidneys, total colesterole, triglyceride levels, LDL-c and antioxidants activity) also led to an increase in HDL-c, in diabetic rats compared with diabetic control. The addition of 20% lupine (bitter and sweet) seeds powder and fenugreek seeds powder and the combination of bitter lupine seeds (10%) and fenugreek seeds (10%) improved oxidative stress and kept liver cells from damage compared to diabetic control