Pharmacological antagonist interventions

Abstract Discoveries of drugs and natural foods were each serendipitous activities, appropriately described in the first use of this word as part of a letter, written from Horace Walpole to Horace Mann on June 28, 1754, after reading a French translation of the Persian story, Peregrinaggio di tre giovani figliuoli del re di Serendippo . It was published earlier, in turn, as an Italian version of the original Persian text by Michele Tramezzino in Venice during 1557, describing in an early detective story the adventures of three young travelers from the Court of Serendip (Sri Lanka). They were in search of a lost camel in an Asian desert, as perhaps an inadvertant symbol of yet undiscovered and/or missing drugs.