Prevention of Irinotecan-Induced Diarrhea by Oral Sodium Bicarbonate and Influence on Pharmacokinetics

Takao Tamura,Yasutake K,Hogara Nishisaki,Takatoshi Nakashima,Kazutugu Horita,Sigeya Hirohata,Arata Ishii,Kenichi Hamano,Nobuo Aoyama,Daisuke Shirasaka,Takashi Kamigaki,Masato Kasuga

Prevention of Irinotecan-Induced Diarrhea by Oral Sodium Bicarbonate and Influence on Pharmacokinetics

2004

Takao Tamura
Yasutake K
Hogara Nishisaki
Takatoshi Nakashima
Kazutugu Horita
Sigeya Hirohata
Arata Ishii
Kenichi Hamano
Nobuo Aoyama
Daisuke Shirasaka
Takashi Kamigaki
Masato Kasuga

Alkalization of the intestinal tract by oral administration of sodium bicarbonate has been reported to be a promising method for preventing delayed diarrhea, a dose-limiting toxicity in patients recei

Keywords:

Immunology
Sodium bicarbonate
Sodium
SN-38
Bicarbonate
Oral administration
Medicine
Irinotecan
Diarrhea
Internal medicine
Pharmacokinetics
Endocrinology
Pharmacology

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations